Metformin is the most widely prescribed oral hypoglycemic medication for type 2 diabetes worldwide. Metformin also retards aging in model organisms and reduces the incidence of aging-related diseases such as neurodegenerative disease and cancer in humans.
In respect to this, how much metformin should I take for anti aging?
Subjects will take 1500 mg of metformin daily for 6 years, with a mean follow-up time of more than 3.5 years [16]. Results from the TAME will provide a widely expected answer to the question whether metformin reduces aging-associated disease and disability in nondiabetic individuals.
Additionally, does metformin slow down the aging process? Based on the increased survival and reduced prevalence of aging-associated diseases in diabetes patients under metformin treatment, it was proposed that the longevity benefits of metformin could be extended to metabolically healthy older people.
Keeping this in consideration, does metformin shorten your life?
By in vitro and in vivo tests we found that metformin shortens life span and limits cell survival when provided in late life, contrary to its positive early life effects.