Drug Levels and Effects
Opinions vary among experts on the advisability of using metronidazole during longer-term therapy while breastfeeding, but some sources recommend discontinuing breastfeeding for 12 to 24 hours after single-dose maternal treatment.
Moreover, can a nursing mother take metronidazole?
Daily 2 g oral doses, normally given for 3 days, are considered to be compatible with breastfeeding. Intravenous administration produces similar maternal plasma and milk levels to equivalent oral doses, although the data are limited. Short-course IV metronidazole is considered to be compatible with breastfeeding.
Keeping this in consideration, can metronidazole decrease milk supply?
Administration of metronidazole by rectal, vaginal, or topical routes produces significantly lower plasma levels, and would therefore be expected to produce correspondingly lower milk levels than after oral administration, and is considered to be compatible with breastfeeding.
Is metronidazole safe for babies?
In newborns with a gestation age <40 weeks, accumulation of metronidazole can occur during the first week of life, which is why the concentrations of metronidazole in serum should preferably be monitored after a few days therapy.
What is the side effect of Flagyl?
Dizziness, headache, stomach upset, nausea, vomiting, loss of appetite, diarrhea, constipation, or metallic taste in your mouth may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. This medication may cause your urine to turn darker in color.
What is Flagyl commonly prescribed for?
Flagyl , known as metronidazole or by the brand name Protostat, is an antibacterial drug that is classified as a broad-spectrum antibiotic. 1 Metronidazole is used to treat certain bacterial infections or protozoal infections (a type of parasite).
Which antibiotics are safe in breastfeeding?
The following antibiotics are all safe to take whilst breastfeeding;
- Amoxycillin, Amoxil ®,
- Azithromycin, Zithromax®,
- Cefaclor, Distaclor®,
- Cefuroxime, Zinnat®
- Cephalexin, Cefalexin, Keflex®,
- Cephradine, Velosef®,
- Clarithromycin, Klaricid®,
- Co-amoxiclav, Augmentin®,
How long does Flagyl take to work?
6. Response and effectiveness. Peak concentrations are reached within one to two hours after dosing; however, it may take up to 48 hours before infection-related symptoms start to abate.
How long do antibiotics stay in breastmilk?
The American Academy of Pediatrics, while rating Flagyl as safe, suggests that nursing women discard their milk for 24 hours after taking a dose of the drug, since a large percent of Flagyl ends up in the breast milk.
Can a breastfeeding mother take flagyl and tetracycline?
Breastfeeding while taking tetracycline:
However, due to low levels in the milk and low absorption by a breastfeeding baby, at this time, there have been no problems reported in babies exposed to tetracycline through breast milk.
Can you pass an infection through breast milk?
The actual risk for transmission of an infectious agent to an infant via a single ingestion of expressed breast milk (the most common occurrence) from another mother is exceedingly low. In this scenario, the CDC recommends treating this as an accidental exposure to a body fluid, which could be infectious.