Current evidence suggests that women may breastfeed while taking warfarin. Trace amounts of warfarin have been found in breast milk however the amounts are too small to reduce the blood clotting in a baby. You will need to make sure that your doctor knows that you take warfarin if you intend to breastfeed.
Moreover, what blood thinners are safe while breastfeeding?
The novel anticoagulants are safe during breastfeeding, so should be the first line of therapy for a breastfeeding mother who develops a blood clot. Warfarin is considered safe during breastfeeding, and should be the first line treatment for oral medication for a breastfeeding mother with a blood clot.
Hereof, is warfarin safe in pregnancy?
Use of warfarin in pregnancy can cause bleeding behind the placenta. This type of bleeding can cause reduced fetal growth, placental abruption, and stillbirth (if severe). The chance of preterm delivery is also higher.
Why is warfarin contraindicated pregnancy?
The inhibition of clotting factors can lead to internal bleeding of the fetus while the inhibition of osteocalcin causes lower bone growth. As well as birth defects, warfarin can induce spontaneous abortion or stillbirth. Because of this, warfarin is contraindicated during pregnancy.
What are the side effects of warfarin?
What are the side effects of warfarin?
- Severe bleeding, including heavier than usual menstrual bleeding.
- Red or brown urine.
- Black or bloody stool.
- Severe headache or stomach pain.
- Joint pain, discomfort or swelling, especially after an injury.
- Vomiting of blood or material that looks like coffee grounds.
- Coughing up blood.
How does warfarin eliminated from the body?
Excretion: Warfarin is primarily eliminated as metabolites by glomerular filtration in the kidney (92% via urine).
What causes blood clots in breast milk?
Vascular engorgement
Blood in your breast milk can also be caused by rusty pipe syndrome, or vascular engorgement. This results from an increase in blood flow to the breasts shortly after giving birth. Your first milk or colostrum may have a rusty, orange, or pinkish color.
Is it safe to take diclofenac while breastfeeding?
Diclofenac and breastfeeding
You can take diclofenac while breastfeeding. Only very small amounts get into breast milk which are unlikely to cause side effects in your baby. Many breastfeeding mothers have used it without any problems.
What is the half life of warfarin?
Pharmacokinetics. The half-life of racemic warfarin ranges from 20 to 60 hours. The mean plasma half-life is approximately 40 hours, and the duration of effect is two to five days. 10 Thus, the maximum effect of a dose occurs up to 48 hours after administration, and the effect lingers for the next five days.