The most common adverse effects of modafinil are headaches, nausea, nervousness, rhinitis, diarrhoea, anxiety and insomnia [27]. In rare cases high doses of modafinil may also induce psychosis [31]. Modafinil has been found to enhance some aspects of cognitive performance in the laboratory.
Besides, does modafinil damage the brain?
Modafinil’s exact mechanism is unclear, though it affects many neurotransmitter systems in the brain. Some studies suggest it may enhance performance on complex tasks in healthy individuals; however, no long-term studies have tested whether modafinil prevents cognitive decline or dementia.
Also, does modafinil affect memory?
These data suggest that modafinil has similar effects on memory as the classical psychostimulants but acts more specifically on hippocampus-dependent memory.
Who should not take modafinil?
You should not use modafinil if you have ever had an allergic reaction or skin rash while taking modafinil or armodafinil (Nuvigil). Modafinil can cause skin reactions that may be severe enough to need treatment in a hospital.
Has anyone died from modafinil?
There do appear to be some reports of death resulting from modafinil overdose when taken in combination with other drugs; however, most sources indicate that there are no valid reports of death occurring by an overdose of modafinil taken alone.
Is modafinil good for depression?
For both subgroups, all three depression rating scales showed a significant improvement following 2 weeks and 3 months of modafinil treatment. This chart review provides preliminary evidence that modafinil treatment may be beneficial to those with major depression, even when unresponsive to other treatments.
Why would a doctor prescribe modafinil?
Modafinil is used to help people who have narcolepsy, obstructive sleep apnea/hypopnea syndrome (OSAHS), or shift work sleep disorder (SWSD) to stay awake during the day.
What happens if you take too much modafinil?
The most frequently reported clinical effects were tachycardia, insomnia, agitation, dizziness, and anxiety. A suicide attempt with modafinil overdose has not been described before.
Can modafinil make you angry?
Signs of Modafinil misuse can include insomnia, irritability, anger and mood swings. Withdrawal symptoms may occur when people who have been taking it for a while stop treatment. These symptoms can include lethargy, anxiety, anhedonia (the inability to experience pleasure) and insomnia.
Is modafinil hard on the liver?
Hepatotoxicity. In clinical trials, modafinil and armodafinil were associated with a low rate of serum aminotransferase and alkaline phosphatase elevations (<1%). Furthermore, despite widescale use, there have not been reports of clinically apparent liver injury due to modafinil or armodafinil.
How long can you stay awake on modafinil?
In trials on healthy people, modafinil allowed users to stay up for almost two days while remaining nearly as focused, alert and capable of problem-solving as the well-rested. After eight hours of sleep, Garreau writes, users can rise and go another 40 hours.